ARV Almirante Brión (F-22) is the second ship of the Mariscal Sucre-class frigate of the Venezuelan Navy.

In general terms, their appearance and equipment is similar to those built for Peru, except for some differences in electronics and missiles.

Almirante Brión was laid down in June 1977 and launched on 22 February 1979 by Cantieri Riuniti dell'Adriatico at Riva Trigoso.

In 1987, together with other units of the Venezuelan navy, she participated in the confrontation with Colombia which almost resulted in an armed conflict, known in Colombia as the ARC Caldas corvette crisis, in which a dispute relating to the territorial waters of the Gulf of Maracaibo naval forces in the area, and a significant deployment of military means at the border of the two countries.

[1] Between 1998 and 2002, together with her sister ARV Mariscal Sucre, she underwent modernization works at the Ingalls Shipbuilding plants in Pascagoula in Mississippi.