[1] In 2003, four hospitals in the Belgian city of Kortrijk merged: Kliniek Maria's Voorzienigheid (founded in 1937), Onze-Lieve-Vrouwehospitaal (1211), Sint-Niklaasziekenhuis (1958) and Sint-Maartenziekenhuis (1955).

In 2005 the construction of one large hospital facility in the neighbourhood of "het Ei in Kortrijk" started.

AZ Groeninge has a history that dates back to the beginning of the 13th century and is one of the oldest hospitals in Belgium.

AZ Groeninge is a teaching hospital that accommodates training of medical and nursing students and residents and clinical fellows in various specialties.

AZ Groeninge is a large private employer in the Arrondissement of Kortrijk and Eurodistrict Lille–Kortrijk–Tournai metropolitan area.

The Alderman for Social Affairs of the City of Kortrijk (and former MEP), Philippe De Coene, serves currently as President of AZ Groeninge.

It participates in regional managed care networks with neighbouring hospitals such as the Onze-Lieve-Vrouw van Lourdesziekenhuis in Waregem, the Jan Ypermanziekenhuis in Ypres, and the hospitals in Mouscron en Tournai, and the AZ Sint-Jan Brugge-Oostende AV in Bruges.