Alumni cast members include Quinta Brunson, Laci Mosley, and Ashley Nicole Black.

The show has featured guest stars such as Issa Rae, Vanessa Williams, Angela Bassett, Laverne Cox, Nicole Byer, Amber Riley, Miguel, Omarion, Raven-Symoné, Kelly Rowland, Tia Mowry, Tahj Mowry, Gabrielle Union, Kyla Pratt, Wanda Sykes, Yvette Nicole Brown and Patti LaBelle.

A Black Lady Sketch Show premiered with a season of six episodes on August 2, 2019, to "universal acclaim" according to review aggregator Metacritic.

Fun and games lead to tension, as Robin, Ashley, Quinta and Gabrielle are stuck in a house after an end-of-the-world event.

A perpetually late-to-work Shayla decides to forgo her morning makeup routine, to her coworker Toni's dismay.

A 1930's groupie, Feather Atwood, sets her sights on Negro league baseball player Satchel Paige.

Quinta, Gabrielle, Robin and Ashley lay down odd rules while playing cards to pass the time.

Dr. Haddassah Olayinka Ali-Youngman, Pre-PhD opines on the COVID-19 pandemic, national racial reckoning, and other social issues.

Salina, informed by psychic Sabrina, goes to confront her old friend Ladonna, who ruined her life due to a 1996 game of MASH.

A historian traces the origins of CP Time to a pair of 19th century Black ladies' encounter with zombies.

Dr. Haddassah Olayinka Ali-Youngman hosts Gabrielle Union on her show Black Table Talk to discuss women in the workplace.

Portia Coché takes offense when the take-out cashier only includes a single set of plasticware with her order.

Robin, Skye, Ashley, and Gabrielle awaken in a penthouse to find that an unknown kidnapper manipulated their perception of the end of the world.

Dr. Hadassah Olayinka Ali-Youngman, pre-PhD visits Luther Vandross Diversity Academy for Career Day.

Dr. Haddassah Olayinka Ali-Youngman Pre-Phd becomes President of the United States, and explains that she used mind-control on the four black women who thought they were the last survivors of the end of the world.

Trinity, the CIA's top agent foils a gang of gun thieves with the help of another woman distracting the men to exercise.

Host Dilly Bird records an episode of Fresh to Def: The Black Culture Murder Podcast.

Actors Behind the Lens Speaking Seriously highlights Noémie Marceau, known for her work as gang leader Elisa, but technical difficulties loom.

In the summer of 2018, Robin Thede invited her close friends and fellow comedians Quinta Brunson, Ashley Nicole Black, and Gabrielle Dennis to help her develop a comedy series.

[24] Thede then pitched the series to HBO as a way to address the dearth of Black women's representation in the American comedic landscape.

[10] On May 24, 2019, it was announced that the show would star Thede along with comediennes Ashley Nicole Black, Gabrielle Dennis, and Quinta Brunson.

Confirmed guest stars include Gabrielle Union, Jesse Williams, Miguel, Skai Jackson, Laz Alonso, Omarion, Kim Wayans, Ayesha Curry, Lance Gross, and Wunmi Mosaku.

[31] Guest appearances include Ava DuVernay, Michaela Jaé Rodriguez, Raven-Symoné, Wanda Sykes, David Alan Grier, Kyla Pratt, Jemele Hill, and Holly Robinson Peete.

[30] New cast members Angel Laketa Moore, DaMya Gurley and Tamara Jade were announced for season 4 on March 21, 2023.

Additional writers for season one are Brittani Nichols, Rae Sanni, Holly Walker, Amber Ruffin and Akilah Green.

A Black Lady Sketch Show seems more interested in creating a whimsical, loving world for its leads.

"[35] Writing for Vulture, Jen Chaney stated: "A Black Lady Sketch Show isn't just funny.

Its sketches are consistently clever and surprising, often concluding with twist endings that add a whole other layer to the jokes that had us rolling a couple of minutes ago.

Club noted the show "has an air of reinvention" and "retains the cohesion, rapid-fire energy, and mix of culturally specific and universal humor that made the first season uproarious and a joy to watch.

[49]" Scherer also complimented the chemistry of the cast members: "they share such an easy rapport, riffing off each other seemingly effortlessly whether the moment is scripted or improvised.