The novel is set in a small religious Mennonite town called East Village, a fictionalized version of Toews' hometown of Steinbach, Manitoba.
The narrator is Nomi Nickel, a curious, defiant, sardonic 16-year-old who dreams of hanging out with Lou Reed in the "real" East Village of New York City.
Nomi, on the other hand, is inquisitive by nature and her compulsive questioning brings her into conflict with the town's various authorities, most notably Hans Rosenfeldt, the sanctimonious church pastor.
Nomi senses that when she graduates from high school, all she'll be expected to do is work at the chicken processing plant and marry a boy from the community and become "good."
Nomi's tragedy is the slow realization that not only will she fail to bring her family together, but she will also have to change her nature to find a place in the town she loves.