A Partnership for National Unity (APNU) is a political alliance in Guyana.

[3] The alliance won 26 of the 65 seats in the National Assembly in the elections.

Prior to the 2015 elections, the APNU formed a joint electoral list with the Alliance for Change.

The combined list won 33 seats, allowing PNC leader David A. Granger to become President.

In 2020, after a controversial election in which the APNU, as part of the APNU/AFC coalition, sought to win through altered poll results, the APNU was defeated and saw the Justice For All Party (JFAP) and Working People's Alliance (WPA) withdraw from the alliance.