A Praed Street Dossier is a collection of detective fiction short stories, essays and marginalia by author August Derleth.

It was an associational collection to Derleth's Solar Pons series of pastiches of the Sherlock Holmes tales of Arthur Conan Doyle.

The two science fiction stories, "The Adventure of the Snitch in Time" and "The Adventure of the Ball of Nostradamus", written with Mack Reynolds, were originally published in The Magazine of Fantasy and Science Fiction.

An earlier edition of the volume was released by Peter Ruber's Candelight Press (1965) as Praed Street Papers.

This article about a collection of mystery short stories published in the 1960s is a stub.