A Troublesome Inheritance: Genes, Race and Human History is a 2014 book by Nicholas Wade, a British writer, journalist, and former science and health editor for The New York Times.

"[9] Wade added that he had asked the letter's main authors, Graham Coop and Michael Eisen, for a list of errors so that he could correct future editions of the book.

[10] Evolutionary geneticist Mark Jobling, one of the signatories to the letter, wrote an opinion piece in the peer-reviewed journal Investigative Genetics explaining that the unprecedented letter was necessary due to both the fallacious nature of Wade's argument and its political ramifications, stating that "Its enthusiastic proponents already include some high profile white supremacists and a former Grand Wizard of the Ku Klux Klan.

"[15] The book was further criticized in a series of five reviews by Agustín Fuentes, Jonathan M. Marks, Jennifer Raff, Charles C. Roseman and Laura R. Stein, which were published together in the scientific journal Human Biology.

"[7] Evolutionary biologist H. Allen Orr wrote in The New York Review of Books that "Wade's survey of human population genomics is lively and generally serviceable.

"[12] Orr comments that, in its second part, "the book resembles a heavily biological version of Francis Fukuyama's claims about the effect of social institutions on the fates of states in his The Origins of Political Order (2011).