In Victorian London, Pamela defies her autocratic father (Donald Crisp), and has a baby out of wedlock with her lover, Gerald Waring Gaythorne (Van Heflin, in his screen debut).
Pamela's pregnant sister Flora (Elizabeth Allan) hears of the death of her young husband, faints, hurting herself, and dies.
Pamela raises her illegitimate daughter as her niece and becomes a crusading journalist for women's rights.
Eventually she agrees to marry diplomat Thomas Lane (Herbert Marshall) after being unfairly named as co-respondent in Gaythorne's divorce.
With a box office loss estimated at a hefty $222,000 for RKO, this was Hepburn's third flop in a row which contributed to Hepburn being one of the actors labeled "box office poison" in the infamous 1938 advertisement created by Harry Brandt, president of the Independent Theatre Owners of America.