Abashiri Station is served by the Sekihoku Main Line from Shin-Asahikawa, and the Senmō Main Line from Higashi-Kushiro.

Okhotsk and Taisetsu limited express trains and Shiretoko rapid services terminate at this station.

There is a ticket office (business hours: 05:30 to 23:00), automatic ticket machines, and a travel centre (business hours: 09:30 to 17:30).

This was intended to ensure that prisoners released from nearby Abashiri Prison and returning to their hometowns from the station would not "revert sideways" (横道にそれない) to a life of crime.

The tourist information centre in Abashiri Station handles tickets for tour buses.