Abdul Karim Ali Al-Iryani (/ˈæbdʊl kɑːˈriːm æl ɪriːˈɑːni/ ⓘ; Arabic: عبد الكريم علي يحيى محمد عبد الله الإرياني‎; 12 October 1934 – 8 November 2015; also spelled Al-Eryani) was a Yemeni politician who served as the Prime Minister of Yemen from 29 April 1998 to 31 March 2001.

Born in Iryan, a village in the central highlands of Ibb, in 1934, Al-Iryani belonged to a prominent family that had held government posts in the region for centuries; many of his ancestors and relatives were judges.

- Banned imports of fruits and vegetables which resulted in a self-sufficient production of such commodities saving hard currency and creating hundreds of thousands of jobs in agriculture and trade.

Al-Iryani was a member of the Global Leadership Foundation, a non-profit organisation set up in 2004 by FW de Klerk to support good governance and reduce conflict around the world.

He has been credited with brokering the Arab Spring peace negotiations in 2012, resulting in a transition plan for President Saleh to resign.