The son of Richard Seller of Plymouth, he was born there about 1646, and matriculated at Lincoln College, Oxford as a servitor, 26 April 1662.
He left Oxford without a degree, and took a job, On 11 March 1665 he was ordained deacon by Seth Ward at Exeter; but did not proceed to the priesthood until 22 December 1672, when he was ordained by Bishop Anthony Sparrow in Exeter Cathedral.
Refusing the oaths to William III and Mary II, the new sovereigns, he was deprived of the vicarage, and his successor was admitted to it on 2 September 1690.
To the Bodleian Library, he gave a manuscript of the end of the 15th century, containing William of Malmesbury's De Gestis Pontificum and the Chronicon Lichfeldense.
He probably also wrote A Letter to the Author of a late paper entituled “A Vindication of the Divines of the Church of England” in defence of the “History of Passive Obedience” (anon.