Abermule (Welsh: Aber-miwl) is a village lying on the River Severn 6 km (4 miles) northeast of Newtown in Powys, mid Wales.

The A483 Swansea to Chester trunk road, the Cambrian Line railway, connecting Aberystwyth to Shrewsbury, and the Montgomery Canal, close to the river, all pass through Abermule.

Abermule had earlier been the junction for a short branch railway to Kerry, closed in 1956.

The Abermule train collision on 26 January 1921 killed 17 passengers, including a Cambrian Railways director, Lord Herbert Vane-Tempest of Machynlleth.

Abermule is served by regular bus services to Llanidloes, Montgomery, Newtown, Rhayader, Shrewsbury, and Welshpool.