Both former presidents Ricardo Joaquín Alfaro Jované and Ernesto de la Guardia were members of the academy.
As a member of the Association of Academies of the Spanish Language, this institution is dedicated to promoting the dissemination of significant Panamanian publications and books.
It is tasked with developing a lexicon of accepted Panamanianisms, including neologisms and archaisms, complete with citations and annotations.
These are submitted to the Royal Spanish Academy (RAE) for potential inclusion in future editions of the Official Dictionary of the Language.
In Panama, the Academy of the Spanish Language conducts various activities including organizing conferences on linguistic, literary, and humanistic topics.