[1] The Academic College of Tel Aviv-Yafo was established in 1994 as a joint initiative of Tel Aviv University, Tel Aviv-Yafo Municipality and the Planning and Budgeting Committee of the Council for Higher Education as a public college.

[1] The inaugural president of the college was Professor Elazar Kochva [he], a zoologist affiliated with Tel Aviv University and one of the college's founding proponents, served in this role until 2000.

The current campus of the college was constructed on the site formerly occupied by the remains of the Eisenberg Hospital in Yafo.

[4][5] The college offers bachelor's degree studies in computer science, economics and management, information systems, psychology, nursing, and philosophy-economics-political combined degree (PAKAM).

Master's degree studies are held in computer science, information systems, psychology, science, business administration, consulting and organizational development, and family studies.