[5] Acanthomeridion was a 35 mm-long animal, with 11 segments ending in rear-facing spines.

[5] More recently discovered specimens of the species Acanthomeridion anacanthus have paired gut diverticula as have been seen in artiopods.

As limbs have not been found, it is uncertain whether Acanthomeridion was a seafloor-dweller or a swimmer.

Acanthomeridion is considered a primitive member of Artiopoda.

Some studies have put it as having affinities with petalopleurans or xandarellids, but a more recent study by Hou, Williams et al. including the more recently discovered specimens suggest that it is the most basal member of the clade.