Achilleas Mamatziolas (Greek: Αχιλλέας Μαματζιόλας; born November 12, 1971, in Thessaloniki), is a retired Greek professional basketball player.
Mamatziolas started his career from the amateur team Propontida Thessaloniki.
Mamatziolas moved to Iraklis the same year, as an exchange for Lefteris Kakiousis transfer.
Mamatziolas played with Greek national basketball team in 1993 Mediterranean Games, and won the fourth place.
He also played at FIBA Under-21 World Championship 1993.