Rosenthal–Kloepfer syndrome, is a cutaneous condition characterized by abnormal growth of bone and skin, coupled with clouding of the cornea.
[2] Another name for the condition is Acromegaly-cutis verticis gyrata-corneal leukoma syndrome.
Presenting symptoms include unilateral or bilateral opacification of the cornea, which progressively involves the whole structure.
Visual disturbance secondary to corneal opacification is often the presenting symptom.
Other symptoms include furrowing of the scalp, enlargement of the bony portion of the eyebrows, and disproportionately large hands.