[1][2][3] It has been measured in coagulation testing to evaluate coagulation, thrombosis, and other cardiovascular complications.
[2][3][4] It is a marker of thrombin generation and indicates hypercoagulability.
[1] Ethinylestradiol-containing birth control pills have been found to increase levels of APC-PCI to a similar degree as thrombin–antithrombin complex (TAT) and to a greater extent than D-dimer.
[5] However, only APC-PCI was able to differentiate between a second- and third-generation birth control pill.
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