He still holds the team records for lowest opponent batting average (.153) and fewest hits allowed (25).

[3][4] The Detroit Tigers called Wilk up to the majors for the first time on May 24, 2011 when Phil Coke was placed on the 15-day disabled list with a bone bruise in his right foot.

[5] On May 26, 2011, Wilk made his major league debut against the Boston Red Sox, relieving Max Scherzer in the middle of the third inning.

[6] On May 28, 2011, Wilk was optioned to Triple-A Toledo to make room for recently acquired David Purcey.

[13] On January 12, 2017, Wilk signed a minor league contract with the New York Mets and was invited to spring training.