In September 2022 plans were announced by the Government of South Australia to build a new facility in Park 27, on the site of the Thebarton Police Barracks.

Initially funded by a number of wealthy patrons, subscriptions, fund-raising, and government grants, it was first intended only for poor and destitute children.

[1] ACH ran the Queen Victoria Convalescent Home for Children at Mount Lofty from 1898 until the 1940s,[1] Mareeba Babies' Hospital in Woodville between 1951 and 1960,[5] and it purchased Estcourt House at Tennyson, relinquishing it in 1978.

[1] The 10,000-square-metre (110,000 sq ft) site, which includes a tower overlooking Victoria Park / Pakapakanthi as well as a heritage-listed building next door, was purchased by the Burnside War Memorial Hospital in late 1996 from Healthscope Ltd, for around A$2.5 million.

[13] As of April 2023[update] the children's wards include:[14] As of April 2023[update] the women's wards include:[15] The WCH Paediatric Emergency Department is open 24 hours, 7 day a week and is located on the ground floor, with access from Kermode Street, Sir Edwin Smith Avenue and Brougham Place.

[16] In September 2022 plans were announced by the Government of South Australia to build the new WCH in Park 27, on the site of the Thebarton Police Barracks.

The barracks comprise 10 buildings which are state heritage-listed, which would be demolished in order to allow construction ofths hospital, planned for opening around 2030–31.