She wrote more than fifty stage pieces in an array of genres: melodramas, pantomimes, farces, comic operettas, historical dramas, and adaptations, as well as translations.

This was the first of many of Dickens's early works adapted for the stage of the Adelphi, including The Pickwick Papers as William Leman Rede's The Peregrinations of Pickwick; or, Boz-i- a-na, a three-act burletta first performed on 3 April 1837, Frederick Henry Yates's production of Nicholas Nickleby; or, Doings at Do-The-Boys Hall in November and December 1838, and Edward Stirling's two-act burletta The Old Curiosity Shop; or, One Hour from Humphrey's Clock (November and December 1840, January 1841).

Dramatisations of Dickens continued to be performed, including A Christmas Carol; or, Past, Present, and Future opening on 5 February; and Beckett's The Chimes: A Goblin Story of Some Bells that rang an Old Year out and a New One In.

[3] The old theatre was demolished, and on 26 December 1858, The New Adelphi was opened and was considered an improvement on the cramped circumstances of the original, which had been described as a "hasty conversion from a tavern hall, permanently kept in its provisional state".

The interior was lighted by a Stroud's Patent Sun Lamp, a brilliant array of gas mantles passed through a chandelier of cut-glass.

The building was renovated in 1879 and again in 1887 when the house next door, along with The Hampshire Hog in The Strand and the Nell Gwynne Tavern in Bull Inn Court, were bought by the Gattis in order to enlarge the theatre.

It was named the 'Royal Adelphi Theatre' and re-opened with the hit musical Ever Green, by Lorenz Hart and Richard Rodgers, based on the book Benn W. Levy.

In 1993, Andrew Lloyd Webber's Really Useful Group purchased the theatre and completely refurbished it prior to the opening of his adaptation of Sunset Boulevard.

Michael Grandage's revival of Andrew Lloyd Webber's Evita replaced the show, beginning previews on 2 June 2006 before completing a twelve-month run on 26 May 2007.

The actor playing Joseph, Lee Mead, was cast by winning the BBC television show Any Dream Will Do, and starred alongside Preeya Kalidas and Dean Collinson.

[citation needed] 9 March 2010 saw the premiere of the Andrew Lloyd Webber musical, Love Never Dies, which closed on Saturday 27 August 2011.

[citation needed] Sweeney Todd, the Demon Barber of Fleet Street began a limited season at the Adelphi from 10 March to 22 September 2012, transferring from the Chichester Festival Theatre, starring Michael Ball and Imelda Staunton.