A former Member of the National Assembly for Garissa Township Constituency, Duale served as the Majority Leader of the National Assembly under the Jubilee Party in the 11th Parliament from 2013 to 2017 and in the 12th Parliament from 2017 to 2020, when he was ousted for perceived disloyalty to former President Uhuru Kenyatta, the Jubilee Party leader.

He then enrolled in Garissa High School where he received his Kenya Certificate of Secondary Education (KCSE) in 1985, and later joined Moi Forces Academy, Nairobi for his Kenya Advanced Certificate of Secondary Education (KACSE), which he completed in 1987.

[9] Duale has served as a representative of the Dujis Constituency in the National Assembly of Kenya since the 2007 parliamentary elections.

[11] During his time as leader of the majority, Duale was the sponsor of an unsuccessful 2018 bill that would have reserved one in three seats in parliament for women.

[12] Early in his tenure as Cabinet Secretary for Defence, Duale officially deployed troops to eastern Democratic Republic of Congo to join an East African Community Joint Regional Force aiming to combat armed groups in the region.