Adolf Jarisch (February 15, 1850 – March 21, 1902) was an dermatologist from the Austro-Hungarian Empire who specialized in the care of venereal disease.
Jarisch noticed unexpected illness and worsening of skin lesions in some syphilitic patients immediately after being treated with mercury.
The patients would experience fever, nausea, and vomiting, and their lesions would worsen before eventually abating and healing.
It usually begins within a few hours of the first dose and causes an initial rise in temperature, pulse rate and blood pressure, then followed by marked vasodilation and sweating, which can result in shock.
[1] Among his numerous publications is Die Hautkrankheiten, an influential book on skin disorders that was included in Carl Nothnagel's Handbuch der speciellen Pathologie und Therapie.