Malori was the lanterne rouge of the 2010 Tour de France, finishing almost four and a half hours behind winner Andy Schleck (Team Saxo Bank).

[4] On 23 January 2016, at the Tour de San Luis, Malori suffered a severe crash as he was leading the peloton.

His front wheel was caught in a crack on the road and he flew over his bike, crashing head-first.

Reports suggested that doctors had found the head trauma not to be a result, but rather the cause of the crash, citing a possible aneurysm.

[7] Malori announced his retirement from professional cycling on 10 July 2017, as a result of the injury.