She gave hundreds of performances in the province, frequently participated in radio broadcasts, and, using the pen name Francine, contributed articles to French-language newspapers and magazines.

[6][2] She also performed for radio stations such as CKAC (Montreal) and CBOFT (Ottawa) in Canada, in New York for French-Canadian communities, and at the studio of French composer Charles Lagourgue.

[2] She began incorporating Indigenous motifs and folklore into her repertoire and performed songs collected from Gitxsan, Huron, Kootenay, Sioux, and Tuscarora nations.

[11][12] Roy-Vilandré claimed that, in recognition of her commitment to preserving culture, the Mohawks of Kahnawake gifted her the name Yohadio (meaning "clear voice in the woods" and occasionally attributed as "Yodahio" or "Princesse Ichadio" ) and made her an honorary member of the community in 1934.

[1] The couple settled in the small village of La Tuque where Joseph ran a medical practice while Adrienne organized benefit concerts for local causes.