She was the daughter of Jean de Noailles and Henriette Anne Louise d'Aguesseau.

[1] On 11 April 1774, she married Gilbert du Motier, Marquis de Lafayette, who left France in 1776 to volunteer in the American Revolutionary War where he served under General George Washington, then later became a key figure in the French Revolution of 1789.

She was a great-granddaughter of Françoise Charlotte d'Aubigné, niece of Madame de Maintenon.

Not wanting to endanger ties with the United States, France abruptly reversed its verdict and did not execute her.

The Marquise de LaFayette died on 25 December 1807 and is buried in the Picpus Cemetery in the 12th arrondissement of Paris.