When MOHR questioned the need for a center such as Affirmations, the organization was moved to its second home a Detroit building owned by inaugural board members Sue Pittmann and Christine Puckett.

[1][2] The center hired its first executive director, Jan Stevenson, an inaugural board member and later board president, in 1991 and expanded its programming to include hosting local LGBT groups and a program for local LGBT youth, funded by a US$150,000 (equivalent to $325,682 in 2023) gift from the estate of Carl Rippberger following his death.

[3] The center opened an art gallery in 1992 named after Pittmann and Puckett, who were murdered in May 1992[3] in an apparent hate crime by a neighbor.

[3] Leslie Thompson became executive director in 2000, expanded programming to include health services and civic engagement, and oversaw the construction and opening of a new building to house the center.

After being at the LA LGBT Center from his departure until 2019, Antonio David Garcia returned to the helm as executive director in May 2019.

[8] Affirmations offers services and multi-use facility space to the LGBTQ population in its surrounding communities.

[2][9] The facility was designed to be environmentally friendly and includes a cyber center, a two-story art gallery, an outdoor rooftop sky deck, and a library.