The terra cotta cougar and bronze school seal, located in the lobby, were donated by the Classes of 1961 and 1962, respectively.

The commons was made possible by a million-dollar donation from Affton High School alumni Bill ('63) and Nancy ('65) Thompson.

A new athletic complex, which included a new football field, bleachers, all-weather track and lights made its debut at the start of the 2004–2005 school year, with contributions from actor and alumnus John Goodman.

[5] On August 12, 2010, the original high school building was added to the National Register of Historic Places.

At the start of the 2020–2021 school year with students remotely learning the district hired a full-time coach for the team.