The main campus is located 17 kilometres (11 mi) northwest of Mutare, the fourth largest city in Zimbabwe, on a 1,542 acres (6.24 km2) rural site with 36 buildings.

The Africa University Development Office located in Nashville, Tennessee,[5] has the primary responsibility to raise funds for the permanent endowment as well as for capital projects.

A 30-member board of directors chaired by Bishop Marcus Matthews governs Africa University.

Professors and policy makers comprise permanent and visiting educators from the United States, Europe, and around the world.

The 32 buildings include 12 dormitories, 12 senior staff housing units, a chapel, and a state-of-the-art library complex.

Recently the Kent M. Weeks Archives[6] was opened to collect all university and United Methodist Church records which are deemed to be of historic and research value.

At the undergraduate level, it has a full-time 4-year programme leading to degrees in accounting, economics, and management, marketing and computer science.

It also offers trainings and short courses for lawyers, civil servants and policy makers.

It has various partners including World Intellectual property organization (WIPO) and the Open Society Initiative in Southern Africa (OSISA) The Departments of Humanities and Social Sciences offer three- and four-year full-time degree programs, in the form of either a Bachelor of Arts or Bachelor of Social Sciences with specialisation in English, Environmental Studies, French, History, Music, Portuguese, Psychology, Sociology, or Religious Studies.