Cameroon, Egypt, Algeria, Tunisia and Morocco have the largest number of winning teams, with three clubs from each having won the title.

Al Ahly is the most successful club in the competition's history, having it a record 12 times, including the most recent season and are the current African champions, having beaten Espérance de Tunis 1–0 on aggregate in the 2024 final.

[2] The 1966 edition introduced the two-legged 'home and away' final, which saw another Malian team AS Real Bamako take on Stade d'Abidjan of Ivory Coast.

Real Bamako won the home leg 3–1 but it all came apart for them in the away game in Abidjan as the Ivorians went on to win 4–1 to take the title 5–4 on aggregate.

[3] In 1967 when Asante Kotoko of Ghana met TP Mazembe of the Democratic Republic of the Congo (or the DRC for short), both matches ended in draws (1–1 and 2–2 respectively).

In between the Cameroonian victories the honor was shared with another team enjoying a golden age, Guinean side Hafia Conakry, who won it three times during this period (1972,[10] 1975[11] and 1977[12]) Apart from the introduction of the away goals rule, very little changed in this competition until 1997, when CAF under Issa Hayatou took the bold step to follow the lead established a few years earlier by UEFA by creating a league/group stage in the tournament and changing the name to the CAF Champions League (in line with UEFA's own Champions League).

[19] Tunisian teams broke into the winners' circle with Étoile du Sahel winning the 2007 edition after being a losing finalist in 2004 and 2005.

[22][23] ASEC Mimosas from Ivory Coast and Accra Hearts of Oak from Ghana added two championships for West Africa.

[28][29][30] The 2020–21 season was played behind closed doors due to the COVID-19 pandemic in Africa in line with global football leagues and competitions.

The CAF Champions League remains Africa's premier club competition, boasting the highest prize money on the continent.

[42] In 2008, CAF put a value of €100 million for a comprehensive and long-term package of its competitions when it opened tenders for a new sponsor, which was scooped up by French telecommunications giant Orange through the signing of an eight-year deal the following year in July, whose terms were not disclosed.