The film stars Myron Healey, Karin Booth, John Kellogg, Lawrence Dobkin, Ross Elliott and James Edwards.

[4] At a military outpost in Africa, Sergeant Drover (John Kellogg) kills his commanding officer, robs the camp safe and runs into the jungle.

Months later, U.S. Army Intelligence assigns Captain Kirby (Myron Healey) to investigate a message from a western doctor (Ray Bennett), who runs a medical clinic in a remote area.

Believing that the killer is hiding near the clinic, the Kirby arranges to be transported upriver to search for the murderer and return him to stand trial with Rene Carvel (Ross Elliott) of the French African Corps as his guide.

After burying the doctor and closing the clinic, the team begin the difficult journey back to the coast with Clark's assistant, Ann Davis (Karin Booth), and the handcuffed murderer.