Agnese Maffeis (born 9 March 1965, in Bergamo) is an Italian discus thrower and shot putter.

She won six medals, at senior level, at the International athletics competitions.

At the Mediterranean Games she won gold medals in shot put in 1987 and 1993 and in discus in 1991 and 1993.

Her personal best throw currently stands at 63.66 metres, achieved in June 1996 in Milan.

Agnese Maffeis has won 38 times the individual national championship (Italian all-time record-woman).