That same year, she made her television debut in Polsat's comedy mini-serial Gosia i Małgosia [pl].

She gained national fame for her roles as Maria "Mariola" Weiss-Korzycka in the TVP2 medical drama series Na dobre i na złe (2001–2009) and as Franciszka Zofia "Frania Maj" Skalska in TVN's comedy series Niania (2005–2009; Polish adaptation of CBS's The Nanny).

She won nine Telekamery nominations in the actress category, winning twice (2006,[2] 2008) and taking second place four times (2005,[3] 2007,[4] 2009,[5] 2015[6]).

[7] In 2007, she received the Star of Smile at the VIII Festival of Good Humor in Gdańsk and two Golden Horseshoes at the Cieszyn Festival "Wakacyjne Kadry" for the best female role in a comedy series (Niania) and the best female role in a sensational series (Fala zbrodni).

In an interview with Gazeta Wyborcza in October 2022, Dygant declared herself to be a feminist and a supporter of the right to abortion.