Some significant structures are among those located within the Historic District include the James B. Dudley Memorial Building and Harrison Auditorium.

[3][4] By an act of the General Assembly of North Carolina, the Agricultural and Mechanical College for the Colored Race was established on March 9, 1891, as an annex to nearby Shaw University in Raleigh.

[5] The university is also a leading producer of African-American psychology undergraduates, minority certified public accountants, landscape architects, veterinarians, and agricultural graduates.

[9] The building originally housed the college's schools of Agriculture and Home Economics on the first floor; the departments of Biology and Chemistry on the top level; with the Dairy Science laboratory located in the basement.

The three-story symmetrical rectangular building, with full basement, features 20,672 square feet of office and classroom space.

Slightly recessed corbelled panels, ornamented by herringbone brickwork and a center, diamond-shaped white stone, stretch above the second story windows.

Noble Hall's interior has been mostly unchanged as well, as the building still retains its original plaster walls, molded door and window surrounds.

Another distinctive feature of the building is the carved and incised stone name panel above the non-functional balcony that extends to surround the center third story windows, in addition to retaining its original double-leaf main entrance door.

The interior was also remodeled and the original high-ceilinged dining area was divided into two floors; an open string staircase with metal railings and a passenger elevator were installed to give access to the mezzanine-level offices.

[15] The building originally housed the college's administrative offices, in addition to an auditorium and library on the main and top levels respectively.

The building also features a broad sweep of fifteen steeps to the main entrance, smooth-face blocks defining a five-bay entrance, intricately carved lintels and acroteria, full classical entablature, splayed arches with keystones over the eight-over-twelve sash windows, and a hexastyle portico with an incised frieze.

The exterior of the building has been virtually unchanged with the exception of the entrance doors, which are now made of double-leaf metal trimmed plate glass.

The flat-roofed two-story building features seven-bay main entrance with the bays defined by plain brick pilasters with simply molded stone bases and capitals.