Some of the earliest major projects by Landa Verdugo were public hospitals for the Mexican Social Security Institute (IMSS) in cities such as Delicias, Chih., and Puebla, Pue., built between 1952 and 1956.

The experience gained in these projects would prove valuable when, in 1959, the government requested from his firm the design of a network of fifty-five health facilities in Mexico City.

The project, funded by the Inter-American Development Bank and inaugurated in 1964, consists of 76 four-story slabs in a large plot of land surrounded by wide avenues and with no internal circulations for cars.

The Ejército Nacional unit, finished in 1974, is of special interest because it was built on an unused plot of land inside a city block.

This project was part of a strategy by INFONAVIT, the country's main public housing agency, called "Aprovechamiento de terrenos baldíos urbanizados" (Taking advantage of abandoned urban plots).

The commission included the design of the urban layout as well as housing, commercial spaces and the facilities for two of the factories that would operate in the new city.

Hired by the Bank of Mexico, the architect was a member of the committee that selected the sites for new tourist centers in the Mexican coast.

The master plan of Cancún consists of a 12-kilometer strip of hotels on a narrow island surrounded by the Caribbean on one side, and a lagoon on the other.

Other notable projects by architect Agustín Landa Verdugo include the French Parish in Mexico City, for the French Catholic Community, the original facilities of the National Free Textbook Commission (CONALITEG) of the Secretariat of Public Education, and an unbuilt proposal from 1967 to build a new international airport for Mexico City in the town of Zumpango.

In 1990, Agustín Landa Verdugo received the silver medal in the first Mexican architecture biennale for a convent built in Huixquilucan.