[3] Ahmed Hassan started his professional football career as a right-back at Aswan Club in the Egyptian lower divisions.

After Hassan was named "Best Player of the African Cup of Nations 2006" he met Ziyad Abou Chair who gave him licence to play in foreign countries;[5] Fulham, Rangers, Newcastle United, and Espanyol were reportedly interested in signing him.

Anderlecht, the Belgian First Division champions, on a free transfer after choosing not to extend his contract with Beşiktaş, which ended in 2006.

His position in the midfield was in front of Lucas Biglia and Jan Polák, just behind the strikers Serhat Akin and Nicolas Frutos.

Ahmed Hassan chose to move to Egyptian club Al Ahly to end his career in Egypt, signing a three-year contract as of May 2008.

In September 2010 he suffered a career-threatening injury in an African Cup of Nations qualifier against Sierra Leone that would keep him away from the fields for six months.

When the league was stopped in February due to the Port Said Stadium disaster, Hassan had played in all 15 games for Zamalek finishing as top scorer of the team with 7 goals.

[6] On 31 January 2010, Hassan picked up his fourth Africa Cup of Nations winners's medal as Egypt defeated Ghana 1–0 in the final.