White Duplex is a historic two-unit residential building at 343 Main Street in the city of Newport, Vermont.

White Duplex stands just west of the main downtown area of Newport, on the south side of Main Street roughly midway between 3rd Street and Governor Drive.

It is a 2+1⁄2-story wood-frame structure, with a cross-gabled roof and an exterior clad in a combination of wooden clapboards and decorative cut shingles.

The center bay has a single sash window on the ground floor, and none on the second.

Most of its documented occupants have been working-class laborers, but it was also occupied early in the 20th century by Leon Colodny, a German-Russian immigrant who owned one of Newport's downtown commercial blocks.