The 5th constituency of the Aisne is a French legislative constituency in the Aisne département.

Aisne's 5th constituency covers the southern portion of the department, the area is centred on Château-Thierry on the river Marne.

Politically the seat elected conservatives for all the Fifth Republic with the exceptions of during the Mitterrand years between 1981 and 1993 and after the 2012 election.

At the 2012 election a National Front candidate secured a place in the 2nd round splitting the right's vote and allowing the election of Jacques Krabal of the left leaning PRG.

Krabal subsequently switched to the centrist La République En Marche!.