[20] Aknaf Beit al-Maqdis battled the Islamic State of Iraq and the Levant, backed by al-Nusra Front, in April 2015 and lost 90% of its territory in Yarmouk Camp.

[16][17][21] As result, Aknaf Beit al-Maqdis disintegrated, as the group was officially absorbed into the Syrian government forces, while many of its members defected to the Al-Nusra Front and ISIL.

[23] In early 2015, amidst its political disintegration, the UN secretary-general Ban Ki-moon accused the group of being implicated in rape and other forms of conflict-related sexual violence.

Amid this offensive, Aknaf Beit al-Maqdis clashed with the more numerous Palestinian pro-government militias in Yarmouk Camp.

[28] In the 2024 Syrian opposition offensives, the "general leader" of Aknaf Bait al-Maqdis and "dozens" of the group's fighters were freed from Sednaya Prison by rebels.