He played for the Newcastle Knights, where he is the highest try-scorer in their history,[4] as well as the Manly Warringah Sea Eagles in the NRL, and later the Huddersfield Giants in the Super League.

[8][9] On 7 October 2006, Uate represented Fiji in the 2008 Rugby League World Cup qualifying match against the Cook Islands, playing at centre and scoring a try in the 40–4 win at Penrith Stadium.

In 2010, Uate started the season on the right wing due to regular right winger James McManus being injured.

Uate beat numerous defenders to score the try in the Knights 34–18 win at Central Coast Stadium.

[21] In May 2011, Uate was selected for New South Wales in Game 1 of the 2011 State of Origin series, making his debut on the wing in the Blues 16–12 loss at Suncorp Stadium.

On 3 November 2011, Uate won the RLIF's International Winger of the Year Award beating the likes of Jason Nightingale and Jharal Yow Yeh.

[27] On 20 April 2012, Uate played for Australia in the 2012 ANZAC Test against New Zealand on the wing in the Kangaroos 20–12 win at Eden Park.

On 23 September 2012, Uate was selected for the Prime Minister's XIII team again with him scoring the last try of the game in the 24–18 victory over Papua New Guinea in Port Moresby.

[33] On 6 March 2013, after speculation that Uate was going to sign with a Japanese rugby union club, he re-signed with the Knights on a 4-year contract to the end of the 2017 season.

[35] In Round 11 against the New Zealand Warriors, Uate played his 100th NRL career match for the Newcastle Knights in the 28–12 loss at Mt Smart Stadium.

In October 2013, Uate switched back his international eligibility to his native Fiji and he was named in their squad for the 2013 Rugby League World Cup.

[39] In Round 13 against the Wests Tigers, Uate broke Timana Tahu's record for most tries scored for the Newcastle Knights.

In Round 6 against the Cronulla-Sutherland Sharks, Uate scored his 100th NRL career try in the Knights' 22–6 loss at Remondis Stadium.

[52] In round 1 of 2017 season, Uate made his debut for the Sea Eagles in their 12–20 loss at Brookvale Oval against the Parramatta Eels.

[55] In June, Uate signed a 3-year contract with Super League side Huddersfield Giants, starting in 2019.