She is the daughter of Sheikh Mana bin Abdul Hadi Al Hajri, who served as the Qatari ambassador to Jordan.

She is Sheikh Tamim's second wife, as he married his second cousin Sheikha Jawaher bint Hamad bin Suhaim Al Thani in 2005.

Sheikha Al-Anoud and the Emir have five children, three daughters and two sons:[3] On 15 December 2011, in honor of National Day, Sheikha Al-Anoud attended a performance of the operetta Homeland of Freedom And Peace at Al Bayan Primary School for Girls in Doha.

[2] In 2015, the Emir paid 100 million euros to purchase Erbilginler Yalısı in Istanbul, the most expensive house in Turkey, as a gift for Sheikha Al-Anoud.

[4][5] Officially, the purchase was made for Sheikha Al-Anoud's father by a London-based real estate company in order to conceal the Emir's involvement.