He is known for his 10-year run as editor of Marvel Fanfare; his long involvement as writer, penciler, and inker on Peter Parker, The Spectacular Spider-Man; his four-year tenure as West Coast Avengers penciller; and his long stint as the inker of X-Factor.

[4] At one point Milgrom lived in the same Queens apartment building as artists Walter Simonson, Howard Chaykin, and Bernie Wrightson.

He penciled the Guardians of the Galaxy feature in Marvel Presents, which was written by Steve Gerber[6] and Roger Stern.

Milgrom inked the limited series A-Next, J2, Marvel: The Lost Generation, and Thanos.

In 2001 Milgrom was fired from his Marvel staff job when it was discovered he had added hidden slanderous comments against then editor-in-chief Bob Harras in the background of a page in the comic book Universe X Special: Spidey.

He also started to work for Archie Comics on a regular basis, inking a variety of titles.

[15] Beginning in the early 2000s, Al Milgrom freelanced for DC again, providing inks for titles like Mystery in Space (vol.

In 2009, Cleburne: A Graphic Novel, written and pencilled by Justin S. Murphy and inked by Al Milgrom, was nominated for the Independent Book Publishers Association's Benjamin Franklin Awards.