The organization works to build LGBTQ+ communities and promote new ideas about the role of gender and sexual diversity in political activism, civil society institutions, media, and everyday life.

[5] Their activities include a national hotline with a team dedicated to supporting transgender people, local community discussion events about sexuality entitled "Hawamesh", and a training program for leaders in Palestinian institutions such as schools, youth groups, and human rights organizations.

[5] In 2011, Al Qaws, Aswat and LGBTQ activist Sarah Schulman joined to organize a delegation of several LGBT people from the United States to Palestine.

[5] In 2014, Al Qaws co-signed a document with other civil organizations calling for an investigation into alleged Israeli war crimes committed during the 2014 Israel–Gaza conflict.

[11][12][13] On August 17, 2019, the Palestinian Authority spokesperson released a statement claiming to ban Al Qaws' activities in the West Bank.