[5][7] Over the past years, Al Quds University has experienced mounting pressure from the Israeli government, both politically and militarily.

[8] In 2013 alone, the Israeli army launched 26 separate attacks on the university campus in Abu Dis, resulting in 1,769 injuries to students and staff.

In the early weeks of 2014, the Israeli army conducted three additional attacks on the Abu Dis campus.

[10] Staff and students frequently face summonses, arrests, and intimidation, both at the Abu Dis campus and the premises in the Old City, which have been raided and occasionally closed on multiple occasions.

[12] Despite being fully accredited and licensed by relevant Palestinian bodies, and internationally recognized, the Israeli authorities in occupied East Jerusalem, insist that the university obtain Israeli accreditation or face closure and arrests of its administration.

However, Israel has also prevented the university from functioning as a unified entity, forcing it to split into two separate institutions.

Al–Quds University's main campus is located in town of Abu Dis, which borders Jerusalem and have close proximity to the Temple Mount.

[23] There is a small girls' campus in Sheikh Jarrah neighborhood of Jerusalem, which is known as the Hind Al–Husseini College for Women.

[24] It was founded by Hind al-Husseini, a Palestinian activist, who rescued orphaned survivors of Deir Yassin massacre, by Zionist militants.

[26] It was a mansion of her grandfather Salim al-Husayni, which was later converted into an orphanage, named as "Children's Home in Jerusalem".

[28] It is located on the Abdel Hamaid Shoman Street in Jerusalem neighborhood of Beit Hanina.

Bayt Mal Al Quds Al–Sharif Agency, a Moroccan organization have planned to construct a new campus of the university in neighborhood of Beit Hanina.

The upcoming campus also includes stadium, green areas equipped with irrigation systems, rainwater recycling station and experimental farm.

[34] Bard College has dual degree program with Al-Quds University which leads to a bachelor of arts from both institutions.

[35] The partnership, which was first announced in February 2009, is the first dual degree program between a Palestinian university and an American institution of higher education.