He played for eight seasons in the National Basketball Association (NBA) with the Charlotte Bobcats, Toronto Raptors, Brooklyn Nets, Washington Wizards and Los Angeles Clippers.

Anderson, as a college senior, averaged 13.2 points, 5.6 rebounds and 1.7 assists per game, earning All-Big Ten Conference Team honors.

[5] After spending one season with Bologna, Anderson signed with the Russian League club Triumph Lyubertsy in 2008.

On December 21, 2010, Anderson signed with Spanish League club FC Barcelona, the 2009–10 EuroLeague champion.

[citation needed] Some praised his defensive efforts, while others referred to him as a ball-hog, the latter was especially evident after his overtime performance against the Miami Heat on January 24, 2013.

[citation needed] Despite the poor showing, he finished the season with the Raptors before becoming an unrestricted free agent.

[15] Anderson made his debut for the Wizards on February 24, 2016, scoring nine points in 16 minutes against the Chicago Bulls.

On February 10, 2023, Anderson was sentenced to 24 months in prison for his involvement in a health care fraud scheme.

He was arrested in 2021 after he was accused of submitting fraudulent claims and recruiting other players to join the scheme.