[1] Craft was most notable for work as one of nine founders of the Children's Cancer Study Group, focusing his research on paediatric oncology, especially the epidemiology of bone tumours that further led to an oncology research unit which has been involved in aetiological studies and in particular the role of irradiation in the development of childhood cancer.
[2][3] He then undertook an MRC Fellowship, working for a year at the Royal Marsden Hospital in London, before returning to Newcastle.
[6] In 1985, Craft returned to work full-time at the Royal Victoria Infirmary in Newcastle, as a Senior House Officer.
[2] In 1993, he was appointed to the Sir James Spence Chair of Child Health and became responsible for the teaching of undergraduate medical students.
[7] Between 2006-08, Craft, along with Sue Killen, chief executive of St John Ambulance, undertook a major review of palliative care services for children in England for the Secretary of State,[6] eventually producing a report titled Palliative Care for Children and Young People in England.
[4] Craft stated in the letter that it would be difficult to staff the new hospital at Annitsford, due to a shortage of doctors and nurses, and that "develop[ing] in-patient emergency services for children in Cramlington [would] go against all current guidance and defies common sense".