It publishes grammars, dictionaries, folklore collections and research materials, as well as hosting an extensive archive of written materials relating to Eskimo, North Athabaskan and related languages.
The Center provides training, materials and consultation for educators, researchers and others working with Alaska Native languages.
The closely affiliated Alaska Native Language Program offers degrees in Central Yup'ik and Inupiaq at the University of Alaska Fairbanks, and works toward the documentation and preservation of these languages.
In 1974, Michael Krauss published a language map of Alaska, which he later updated in 1982.
In the summer of 2011, the Alaska Native Language Center made an update to Krauss's map.