Bred in three sizes, its weight range is from 5 to 22 pounds as an adult, depending on whether it is a standard, toy, or miniature.

The Toy Alaskan Klee Kai can be up to 13 inches or 33 cm tall and weighs less than 10 pounds or 4.5 kg.

The Miniature Alaskan Klee Kai can be 13–15 inches or 33-38 cm tall and weigh 10–15 pounds or 4.5-6.8 kg.

The Standard size Alaskan Klee Kai can be 15–17 inches or 33-43 cm tall (17-17.5 inches or 43-44.5 cm is still considered a standard size Alaskan Klee Kai, but is a fault) and weigh 15–20 lbs or 6.8-9 kg.

Alaskan Klee Kais are prone to developing juvenile cataracts, liver disease, factor VII deficiency and heart problems.