The singer first gained national recognition in 2018 placing as the runner-up in series ten of the Spanish reality television talent competition Operación Triunfo, behind Famous Oberogo.

After exiting the show, the singer signed a record deal with Universal Music and released her debut studio album Quimera (2019) which peaked on the third position on the PROMUSICAE musical chart, sold more than a twenty thousand copies, charted more than thirty weeks and scored a Latin Grammy nomination for Best Engineered Album.

[5] Pushed by her sister, Reche auditioned alongside her relative to take part of the upcoming season of Operación Triunfo.

The tour (named OT 2018 en concierto) began on February 8 at the WiZink Center and ended in Cádiz in August after the last two shows were cancelled due to low ticket sales.

[19] In April 2020, a live acoustic EP titled Sobre Quimera recorded at the Reina Sofía Museum was released on streaming platforms.

[22] Alternatively, she embarked on a coronavirus-friendly summer concert tour that respected the social distance dictated by the World Health Organization.

[24] Previously she had taken part of the "People in Red" gala in Barcelona, which raised 926,000 euros "to invest them in research projects that are being carried out such as the preventive HIV vaccine, but which also helps other diseases such as cancer or Alzheimer's to benefit".

In November 2019, following a second election within six months in Spain, the singer expressed rejection to the 3,5 million people who had voted for far-right nacionalist political party Vox by saying "you guys are not needed" on Twitter.

[29] Reche spoke about the Catalan independence movement with 20 Minutos and stated that "the Government isn't allowing people to express what they believe in".

[31] In June 2020 she attended the Madrid protest in favor of racial equality and against police brutality and the murder of George Floyd alongside singer and friend Natalia Lacunza.