In March 2008, Skvortsov was assigned to the Expedition 21/22 backup crew as a flight engineer and Soyuz TMA commander.

[3] He traveled to the ISS aboard Soyuz TMA-18 along with fellow Russian cosmonaut Mikhail Korniyenko and NASA astronaut Tracy Caldwell-Dyson, on April 2, 2010, from the Baikonur Cosmodrome in Kazakhstan.

[4] Ending Expedition 24, the Soyuz TMA-18 spacecraft carrying Commander Alexander Skvortsov, Mikhail Kornienko, and NASA astronaut Tracy Caldwell-Dyson undocked from the space station at 10:02 p.m. EDT on September 24, 2010.

After returning to Earth and sharing his experiences to an audience, Skvortsov said "I love spicy food, I make really hot chili sauce myself.

[5] Skvortsov returned to space aboard Soyuz TMA-12M, along with Oleg Artemyev and Steven Swanson, as a flight engineer on the Expedition 39 crew.

[6] Skvortsov launched on July 20, 2019, and arrived to the International Space Station on the same day,[7] joining the Expedition 60/61 crew.

[8] This article incorporates public domain material from websites or documents of the National Aeronautics and Space Administration.